Adrenomedullin, a Multifunctional Regulatory Peptide*
نویسندگان
چکیده
منابع مشابه
Adrenomedullin as a renal regulator peptide.
belongs to the CGRP superfamily. The human ADM precursor (preproADM) is 185 amino acids in length and is processed to 164-amino acid peptide, proADM, and then to a 52-amino acid peptide, the biologically active form of ADM. The genomic DNA of human
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Adrenomedullin is a novel peptide that elicits a long-lasting vasorelaxant activity. Recently, we found high concentrations of adrenomedullin in maternal and umbilical cord plasma and in amniotic fluid in full-term human pregnancy, indicating a role of this peptide during gestation. To investigate the possibility that adrenomedullin is involved in the pathophysiology of preeclampsia, we measure...
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BACKGROUND It has been demonstrated that adrenomedullin, a newly discovered peptide, affects the release of insulin from pancreatic islets cells, suggesting a role in the insulin-regulating system. OBJECTIVE To investigate whether adrenomedullin secretion is modified in patients with insulin-secreting islet cell tumours. DESIGN The study was performed in nine patients with surgically treate...
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ژورنال
عنوان ژورنال: Endocrine Reviews
سال: 2000
ISSN: 0163-769X,1945-7189
DOI: 10.1210/edrv.21.2.0396